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Original Article

Hepatic adenomatosis: MR Imaging Features

Authors:

I De Kock ,

Department of Radiology, General Hospital Sint-Lucas, Ghent, Belgium, BY
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K J Mortelé,

Department of Radiology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston
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B Smet,

Department of Radiology, General Hospital Sint-Lucas, Ghent, Belgium, BE
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P Gillardin,

Department of Radiology, General Hospital Sint-Lucas, Ghent, Belgium, BE
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W Pauwels,

Department of Gastroenterology, General Hospital Sint-Lucas, Ghent, Belgium, BE
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AI De Backer

Department of Radiology, General Hospital Sint-Lucas, Ghent, Belgium, BE
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Abstract

Hepatocellular adenomas are rare benign liver neoplasms that commonly occur in women with a history of oral contraceptives intake for more than 2 years. Hepatic adenomatosis is characterized by the presence of multiple adenomas, arbitrarily > than 10, involving both lobes of the liver, without any history of steroid therapy or glycogen storage disease. Although the adenomas in liver adenomatosis are histologically similar to other adenomas, liver adenomatosis appears to be a separate clinical entity. Adenomas in hepatic adenomatosis may be of the inflammatory, hepatocyte nuclear factor 1alpha-mutated, or beta-catenin-mutated subtype, and accordingly show variable imaging appearances. Hepatic adenomatosis carries the risk of impaired liver function, hemorrhage and malignant degeneration. We report a case with the inflammatory subtype of hepatic adenomatosis in a 39-year-old woman with liver steatosis. The magnetic resonance imaging features using extracellular gadolinium chelates and hepatocytetargeted contrast agents are described.

Keywords: Liver neoplasms,   MR  
How to Cite: Kock, I.D. et al., (2014). Hepatic adenomatosis: MR Imaging Features. Journal of the Belgian Society of Radiology. 97(2), pp.105–108. DOI: http://doi.org/10.5334/jbr-btr.25
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Published on 01 Mar 2014.
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