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Reading: Erdheim-Chester disease detected with 99MTC MDP bone SPECT/CT

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Original Article

Erdheim-Chester disease detected with 99MTC MDP bone SPECT/CT

Authors:

G Ceulemans ,

Department of Nuclear Medicine, UZ Brussel, Brussels, Belgium
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M Keyaerts,

Department of Nuclear Medicine, UZ Brussel, Brussels, Belgium
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L Verbruggen,

Department of Rheumatology, UZ Brussel, Brussels, Belgium
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A Hoorens,

Department of Pathology, UZ Brussel, Brussels, Belgium
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C Boulet,

Department of Radiology, UZ Brussel, Brussels, Belgium
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D Verdries,

Department of Radiology, UZ Brussel, Brussels, Belgium
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M De Maeseneer,

Department of Radiology, UZ Brussel, Brussels, Belgium
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B Ilsen,

Department of Radiology, UZ Brussel, Brussels, Belgium
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H Everaert

Department of Nuclear Medicine, UZ Brussel, Brussels, Belgium
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Abstract

Erdheim-Chester disease (ECD) is a rare non-Langerhans’ cell histiocytosis. Mild but permanent juxta-articular bone pain in mainly knees and ankles is the most frequent associated symptom. Despite the pathognomonic radiographic findings, most cases are still diagnosed by the pathologist. The lesions consist of lipid-storing CD 68 +/ CD 1a – non- Langerhans’ cell histiocytes, most frequently localized in bone but also involving multiple organ systems in the body. We present a case report in which the diagnosis of ECD was established with 99mTc MDP bone SPECT/CT.

How to Cite: Ceulemans G, Keyaerts M, Verbruggen L, Hoorens A, Boulet C, Verdries D, et al.. Erdheim-Chester disease detected with 99MTC MDP bone SPECT/CT. Journal of the Belgian Society of Radiology. 2012;95(4):245–8. DOI: http://doi.org/10.5334/jbr-btr.630
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Published on 01 Jul 2012.
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