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Bone marrow involvement in sarcoidosis

Authors:

F Van Den Bergh ,

Department of Radiology, AZ Sint-Maarten, Duffel-Mechelen, Department of Radiology, University Hospital Ghent (UZ Gent)
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J Wagemans,

Department of Medical Oncology, AZ Sint-Maarten, Duffel-Mechelen
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A Snoeckx,

Department of Radiology, University Hospital Antwerp (UZA), Belgium
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KL Verstraete,

Department of Radiology, University Hospital Ghent (UZ Gent)
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FM Vanhoenacker

Department of Radiology, AZ Sint-Maarten, Duffel-Mechelen, Department of Radiology, University Hospital Ghent (UZ Gent), Department of Radiology, University Hospital Antwerp (UZA), Belgium
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Abstract

A 36-year-old woman presented with joint pain and swelling, not improving with nonsteroidal anti-inflammatory drugs. Plain radiographs of feet, ankles, pelvis and lumbar spine were unremarkable. To rule out seronegative spondylarthropathy, MRI of the sacro-iliac joints (SIJ) was performed. The SIJ were normal, but multiple, nodular zones of bone marrow replacement were seen within the iliac and ischial bones, sacrum and lumbar spine. The lesions were hypointense on T1-Weighted Images (WI) (Fig. A, arrows) and of intermediate to high signal intensity on T2-WI (Fig. B, arrows). Given the young age of the patient and relative minor complaints, sarcoidosis was suspected. Other differential diagnoses included metastatic disease, lymphoma, mastocytosis and widespread granulomatous infectious disease.

How to Cite: Bergh FVD, Wagemans J, Snoeckx A, Verstraete K, Vanhoenacker F. Bone marrow involvement in sarcoidosis. Journal of the Belgian Society of Radiology. 2012;95(6):376. DOI: http://doi.org/10.5334/jbr-btr.735
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Published on 01 Nov 2012.
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