Background: A 55-year-old Caucasian man presented with weight loss, cramping abdominal pains, an increasing abdominal circumference and diarrhea. Physical examination showed no abnormalities besides a puffy abdomen. His past medical history included a recent subcutaneous swelling in the neck, histologically compatible to a benign solitary fibrous tumor. All blood results were within normal limits. Abdominal ultrasonography showed a tumor with diameter of 6.7 cm, probably originating from the pancreas, with ascites and retroperitoneal lymphadenopathy. This was followed by a CT scan. CT scan of the abdomen was repeated following therapy.